Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
CY-09 is a selective, direct inhibitor of the NLRP3 inflammasome used for biochemical and cellular research. It binds the ATP-binding motif of the NLRP3 NACHT domain and inhibits NLRP3 ATPase activity, preventing inflammasome assembly and activation. For research use only.
Selective NLRP3 inhibitor targeting the NACHT domain
Inhibits NLRP3 ATPase activity to block inflammasome activation
High purity compound suitable for biochemical and cellular assays
Available as a solid powder, stable under recommended storage conditions
Supplied in research-scale pack sizes for laboratory experiments
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM. It is for research use only and not sold to patients.
Inhibits the proliferation of MLL leukemia cells with a GI50 of 83 nM.
Shows selectivity towards MLL fusion protein transformed cells.
Binds to menin with a Kd of 6.5 nM.
Leads to strong down-regulation of Hoxa9 and Meis1 gene expression.
Reduces tumor volume in mice xenografts.
Improved exposure and Cmax in blood plasma.
Low clearance and a half-life of about 1.6 hours.
High oral bioavailability (~50%).
Soluble in DMSO.
Soluble in various in vivo protocols, including 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(rac /meso)-Astaxanthin (Standard) is the analytical standard of (rac /meso)-Astaxanthin This product is intended for research and analytical applications rac-Astaxanthin is a carotenoid pigment found primarily in marine animals including shrimp and salmon It is a potent lipid-soluble antioxidant
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Melinamide is an amide derivative of an unsaturated long-chain fatty acid that inhibits cholesterol absorption (reported IC50 20.9 μM). Supplied as an oil or DMSO solution for research use, it is used in biochemical studies of cholesterol uptake and acyltransferase-related pathways.
Molecular formula C26H41NO
Molecular weight 383.61 g·mol⁻¹
Reported activity: IC50 20.9 μM for cholesterol absorption inhibition
Purity 99.9%
Available as oil and 10 mM DMSO solutions in multiple package sizes
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More